【综述2021】无创脑刺激对阿尔茨海默病精神行为症状治疗的研究进展-王祖星.pptx

王祖星等无创脑刺激对阿尔茨海默病精神行为症状治疗的研究进展第4期·73·

Doi:10.3969/j.issn.2096-5516.2022.01.015

无创脑刺激对阿尔茨海默病精神行为症状治疗的研究进展

王祖星闵文蛟蒋富贵肖军(电子科技大学附属医院四川省医学科学院四川省人民医院四川省精神医学中心，四川成都611731)

中图分类号R749.1文献标志码A文章编号2096-5516(2022)01-0073-05

[摘要]阿尔茨海默病(Alzheimersdisease,AD)是老年人中最常见的痴呆类型，往往伴随着很多痴呆的精神与行为症状(behavioralandpsychologicalsymptomsofdementia,BPSD)。近年来，不同类型的无创性脑刺激(noninvasivebrainstimulation,NIBS)技术被广泛用于AD患者的治疗，先前大量的研究表明，经颅直流电刺激(transcranialdirectcurrentstimulation,tDCS)和重复经颅磁刺激(repetitivetranscranialmagneticstimulation,rTMS)都能显著改善AD患者的认知功能。然而，关于NIBS对AD患者BPSD治疗的研究相对较少，结果仍然存在争议。本文就tDCS和rTMS对AD患者BPSD治疗的研究进展做综述。

[关键词]阿尔茨海默病；经颅直流电刺激；重复经颅磁刺激；痴呆的精神与行为症状

ProgressofnoninvasivebrainstimulationinthetreatmentofBehavioralandPsychologicalSymptomsofDementiainAlzheimersdisease

WANGZu-xing,MINWen-jiao,JIANGFu-gui,XIAOJun(SichuanProvincialCenterforMentalHealthy,SichuanAcademyofMedicalSciencesandSichuanProvincialPeoplesHospital,AfiliatedHospitalofUniversityofElectronicScienceandtechnology,Chengdu,Sichuan611731,China.)

[Abstract]Alzheimersdisease(AD)isthemostcommontypeofdementiaintheelderly,whichisoftenaccompaniedbymanybehavioralandpsychologicalsymptomsofdementia(BPSD).Recently,differenttypesofnoninvasivebrainstimulation(NIBS)havebeenwidelyusedinthetreatmentofADpatients.Manypreviousstudiesbothhaveshownthattranscranialdirectcurrentstimulation(tDCS)andrepetitivetranscranialmagneticstimulation(rTMS)cansignificantlyimprovethecognitivefunctionofADpatients.However,therearefewstudiesaboutNIBSforthetreatmentofBPSDinADpatients,andtheresultsarestillinconsistent.Inthispaper,theprogressoftDCSandrTMSinthetreatmentofBPSDinADpatientswillbereviewed.

[Keyword]Alzheimersdisease;Transcranialdirectcurrentstimulatio