大纲放射发光简介显微镜闪烁体表征特性使用人类癌细胞结果线3 sengupta.pdfVIP

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大纲放射发光简介显微镜闪烁体表征特性使用人类癌细胞结果线3 sengupta.pdf

Outline

•Introductiontoradioluminescence

microscopy

•Characterizationofscintillator

properties

•Resultsusingahumancancercell

line

Radioluminescencevs.fluorescence

microscopy

RadioluminescenceFluorescence

ImagesradiotracersImagesfluorescenttracers

Lightsource=anindividualLightsource=single

ionizationtrackfromadiffraction-limitedpoint

radioactiveemission

Resolution~10sofmicronsResolution~1micron

CanimageclinicallyusedCannottypicallyimage

radiotracersclinicallyusedtracers

Principlesofradioluminescence

•Usesthinfilmscintillators(10-100sofm)to

imageradiotracerswithhighresolution

•Canbeusedtoimageradiotraceruptakeon

themicronscale,asacomplementtoclinically

usedtracersinpatients

22μm

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