Alloc-Val-Ala-OH-Allyloxy-carbonyl-L-valyl-L-alanine-生命科学试剂-MCE.pdfVIP

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Alloc-Val-Ala-OH

Cat.No.:HY-W076556

CASNo.:330970-70-2

Synonyms:((Allyloxy)carbonyl)-L-valyl-L-alanine

分⼦式:C₁₂H₂₀N₂O₅

分⼦量:272.3

作⽤靶点:BiochemicalAssayReagents

作⽤通路:Others

储存⽅式:Powder-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性Alloc-Val-Ala-OH(((Allyloxy)carbonyl)-L-valyl-L-alanine)是合成Tesirine的构建块，Tesirine是⼀种临床抗体

-药物偶联物(ADC)吡咯并苯⼆氮卓(PBD)⼆聚体有效载荷。Val-Ala将被组织蛋⽩酶B特异性切割。Alloc基

团对哌啶和TFA处理稳定，但可在温和条件下通过钯催化烯丙基转移轻松去除。

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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