C1-Esterase-Inhibitor-Human-生命科学试剂-MCE.pdfVIP

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C1EsteraseInhibitor(Human)

Cat.No.:HY-P991629

作⽤靶点:Ser/ThrProtease

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性C1EsteraseInhibitor(Human)是⼀种源⾃⼈⾎浆的C1酯酶(C1Esterase)抑制剂。C1EsteraseInhibitor

(Human)是⼀种糖蛋⽩，也是⼀种⾎清蛋⽩酶抑制剂(丝氨酸蛋⽩酶)，可与C1r、C1s和⽢露聚糖结合蛋⽩相

关蛋⽩酶(MASP)共价结合并使其失活。C1EsteraseInhibitor(Human)具有抗炎作⽤。C1EsteraseInhibitor

(Human)可⽤于预防与遗传性⾎管性⽔肿相关的⾎管性⽔肿发作。

REFERENCES

[1].KeatingGM.HumanC1-esteraseinhibitorconcentrate(Berinert).BioDrugs.2009;23(6):399-406

[2].BergerM,etal.UpdateonC1EsteraseInhibitorinHumanSolidOrganTransplantation.Transplantation.2019Sep;103(9):1763-1775.

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