穴位肥大细胞及其颗粒物在针刺镇痛中的作用.pptxVIP

纪念安徽针灸经络研究50周年穴位肥大细胞及其颗粒物

在针刺镇痛中的作用

针灸经络研究回顾与展望国际学术研讨会

Outline穴位肥大细胞在针刺镇痛效应中的作用穴位胶原纤维在针刺镇痛效应中的作用穴位注射组胺的镇痛效应手针和电针穴位信号的启动机制

MastcellsinacupointsandsidewardTHEJOURNALOFSCIENCEHEALING,2008，4（3），170-177

1.Therelationshipbetween

mastcellfunctionandacupunctureeffectAnimalmodel：AA(acutearthritis)RatCompleteFreunds’adjuvant

Acupointselected：Zushanli(ST36)DST36C1.Therelationshipbetween

mastcellfunctionandacupunctureeffect

Treateffect：Easepain，Painthreshold1.Therelationshipbetween

mastcellfunctionandacupunctureeffect

ThedegranulationofmastcellsSDRatsTailFlickModelAnatomyPositionofZusanliAcupunctureInjectiondrugsforpreventdegranulationofMCABDEST36C

Painthresholdofratwhenshieldmastcelldegranulation

1.Therelationshipbetween

mastcellfunctionandacupunctureeffect各组别大鼠痛阈变化率峰值比较（20分钟时）(n=6)Note:*P0.05vs.GroupA;△P0.01,△△P0.05vs.GroupB1;▲P0.01,▲▲P0.05vs.GroupD1

1.Therelationshipbetween

mastcellfunctionandacupunctureeffect穴区组织肥大细胞脱颗粒率统计(n=6)Note:*P0.01,**P0.05vs.ControlGroup;△P0.01vs.AcupunctureGroup.

ResultsfromExperimentStainingofMastCellsinAcupointonRatsMuscleSkinBeforeAcupunctureAfterAcupunctureDegranulationofcellsAfterSDCGStabilizedTHEJOURNALOFSCIENCEHEALING,2008，4（3），170-177

WhatisthekeyfactortodegranulationTheacupunctureeffectispositiverelationshiptothedegranulationofmastcellatacupoint.01Whatiskeyfactorconducethedegranulationofmastcellduringacupuncturemanipulation?02Ourfocusisonthecollagenatacupoint.03

ToobservethefunctionofcollagenfibersinMAanalgesia.7Animalgroupssetting:normalgroup(N):Normalhealthyanimalcontrolgroup(M):AnimalwithAAinjectionofcollagenaseatZusanli(ST36)group(C)manualacupuncturegroupwithrotationmanipulation(R)orlift-thrustmanipulation(L),rotationgroupwithcollagenasepretreatmenttodestroyZusanli(ST36)collagenfibers(CR),lift-th