2025年MCAT生物化学测试卷含解析.docxVIP

2025年MCAT生物化学测试卷含解析

考试时间：______分钟总分：______分姓名：______

PartA:BiologicalandBiochemicalFoundationsofLivingSystems

1.Whichofthefollowingaminoacidsisclassifiedasnonpolarandhydrophobicduetoitssidechainstructure?

A)Lysine

B)Threonine

C)Alanine

D)Aspartate

2.Inthecontextofproteinfolding,whichprocessinvolvestheformationofalpha-helicesandbeta-sheetsthroughhydrogenbondingbetweenthebackboneamidehydrogenandcarbonyloxygenatoms?

A)Denaturation

B)Hydrolysisofpeptidebonds

C)Oxidativephosphorylation

D)Secondarystructureformation

3.WhichmetabolicpathwayisprimarilyresponsibleforgeneratingATPinthepresenceofoxygenbytransferringelectronsfromNADHandFADH2tooxygen?

A)Glycolysis

B)Gluconeogenesis

C)Thecitricacidcycle

D)Theelectrontransportchain

4.Amutationresultsinasingleaminoacidsubstitutioninacriticalenzyme,alteringitsactivesiteandsignificantlyreducingitscatalyticefficiency.Thistypeofmutationismostlikelya:

A)Silentmutation

B)Missensemutation

C)Nonsensemutation

D)Frameshiftmutation

5.Whichofthefollowingisakeyintermediateinbothglycolysisandthecitricacidcycle?

A)Pyruvate

B)Acetyl-CoA

C)Glucose-6-phosphate

D)Oxaloacetate

6.Theenzymehexokinaseplaysacrucialroleinglycolysisbycatalyzingthephosphorylationofglucose.Whichofthefollowingbestdescribestheregulationofhexokinaseactivity?

A)Itisinhibitedbyitsproduct,glucose-6-phosphate.

B)Itisactivatedbyinsulin.

C)IthasaveryhighKmforglucose,requiringhighconcentrationsforsignificantactivity.

D)Itoperatesexclusivelyinthecytoplasmofanimalcells.

7.Whichlipidistheprimarystructuralcomponentofcellmembranes,formingabilayerwherethehydrophobictailsfaceinwardandthehydrophilicheadsfaceoutward?

A)Triglycerides

B)