肾小球疾病专题知识宣讲.ppt

肾小球疾病专题知识宣讲

outlineAnatomyandfunctionGeneralpathogenesisClinicalsyndromesandpresentationSpecificglomerulardiseases

Anatomyandfunction

Anatomy

AnatomyRenalFunctionRemovewastesMaintainhomeostasisSecreteEPO

Anatomy-nephron

GlomerularAnatomyCapillaryLumenEndothelialcellGlomerularbasementmembraneEpithelialcellPodocytes

Structureofnormalglomerularcapillary系膜细胞系膜基质内皮细胞上皮细胞足突

Generalpathogenesis

Whatcausesglomerulardisease?Mostareofimmunologicorigin,andcausedbyimmunecomplexes!

AntibodymediatedGN-

CirculatingImmunecomplexLocation:Mesangialandsub