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阿尔兹海默病静息态研究Resting Brain Connectivity.pdf
Note: This copy is for your personal, non-commercial use only. To order presentation-ready copies for
distribution to your colleagues or clients, contact us at /rsnarights.
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I Resting Brain Connectivity:
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O Changes during the Progress of
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n Alzheimer Disease
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I Hong-Ying Zhang , MD , PhD
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I Purpose: To investigate alterations in functional connectivity in the
R Shi-Jie Wang , PhD
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resting brain networks in healthy elderly volunteers and
Bin Liu , MMed
patients with mild, moderate, or severe Alzheimer Dis-
Zhan-Long Ma , PhD ease (AD).
Ming Yang , PhD
Zhi-Jun Zhang , PhD , MD Materials and This study was approved by the institutional ethics com-
Gao-Jun Teng , PhD , MD Methods: mittee, and informed consent was obtained. Forty-six
patients with AD and 16 healthy elderly volunteers were
prospectively examined. Resting-state functional magnetic
resonance imaging was used to detect alterations in
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