病理学英文课件_6.2MesenchymalTumors_.pptVIP

Section 9 Mesenchymal Tumors 1. Benign (1) Fibroma Grossly: firm, encapsulated masses, whitish Histological: interlacing bundles of mature fibrocytes, fibroblasts, and collagen fibers. Site: commonly in subcutaneous tissue, fascia periosteum ovary * Formatives: tumor like growths of fibrous tissue in the soft tissue, e. g. dermatofibroma, nodular facilities, juvenile aponeurotic fibroma, desmoid fibromatosis, keloid, and palmar fibromatosis (2) Lipoma Gross: lobulated mass with thin capsule, greasy on cut surface, yellowish in color. Histological: composed of mature fat cells. Site: Commonly in the subcutaneous tissue of arms, shoulder, and buttocks (3) Hemangioma Usually congenital but may be acquired. Gross: Portwine colored, soft, poorly defined lesion Histological: Composed of blood vessels, invasive growth partner. Type: ① Capillary type commonly in skin or mucous membrane ② Cavernous type commonly in skin, spleen, liver. (4) Lymphangioma or cystic hygroma Usual congenital Gross: Pale, soft, poorly defined lesion Histological: Composed of lymphatic vessels. (5) Leiomyoma Gross: A single or multiple, firm, circumscribed Histological: Spindle shaped smooth muscle cells, interwoven fibers of fusiform, varying amounts of connective tissue. Site: Commonly in uterus, gastrointestinal tract tongue (6) Osteoma Mainly found in skull and the long bones (7) Chondroma Gross: firm, bluish with fibrous capsule, sometimes central softening with brownish fluid. 2. Malignant (1) Fibrosarcoma The more the cellularity and the number of mitotic figures, the greater the malignancy (2) Rhabdomyosarcoma Type: ① Embryonal rhabdomyosarcoma: Most common type occurs in children often arise in the nasal cavity, orbit, middle ear, prostate, and Para testicular region. Various stages of embryogenesis round and spindled cells in a variably myxoid stroma. ② Alveolar rhabdomyosarcoma Occur in early to mid a