药理学课件__18抗精神失常药.pptVIP

抗精神失常药PHARMACOLOGY OF ANTIPSYCHOTIC DRUGS (NEUROLEPTICS) SOME DEFINITIONS Neuroleptic: synonym for antipsychotic drug; originally indicated drug w/antipsychotic efficacy but with neurologic (extrapyramidal motor) side effects Typical neuroleptic: older agents fitting this description Atypical neuroleptic: newer agents: antipsychotic efficacy with reduced or no neurologic side effects NEUROLEPTICS ON THE UUHSC DRUG LIST TYPICAL NEUROLEPTICS: PHENOTHIAZINES: Chlorpromazine (Thorazine ? ) Thioridazine (Mellaril ? ) Fluphenazine (Prolixin ? ) THIOXANTHENE Thiothixene (Navane? ) OTHER Haloperid