外文资料原文--制备的微孔热塑性聚氨酯为使用.pdfVIP

Fabrication of Microporous Thermoplastic Polyurethane for Use as Small-Diameter Vascular Graft Material. I. Phase-Inversion Method M. T. Khorasani, S. Shorgashti Biomaterial Department, Iran Polymer and Petrochemical Institute, P.O. Box 14965/115, Tehran, Iran Received 26 May 2004; revised 16 January 2005; accepted 23 February 2005 Published online 13 September 2005 in Wiley InterScience (). DOI: 10.1002/jbm.b.30363 Abstract: Fabrication conditions of microporous thermoplastic polyurethane to be used in small-diameter vascular grafts are studied. Porosity variations due to various factors such as concentration of PU solution, composition of coagulation bath, effect of coagulant tempera- ture, and effect of dissolved air in PU solution are discussed. The liquid–liquid phase-inversion process used for preparation of PU films and the mechanism for the formation of microporous films are discussed. Surface and cross-section morphologies of PU films are studied with the use of scanning electron microscopy (SEM), and porosity value and mechanical strength of PU films are also determined. SEM photomicrographs show that PU films prepared in an alcoholic coagulant have uniform porous structure compared to films prepared in water coagulant. Increasing the polymer concentration and coagulant temperature ( 23°C) de- creases the macrovoid formation, as seen in cross sections of PU films. This enhances the tensile modulus of PU films. By using this process adjustment may be made on the morphology and compliance, as they are important factors in design and fabrication of small-diameter vascula