EGFR-TKI在肺癌中的治疗.pptVIP

EGFR-TKI在肺癌一线治疗中的作用 同济医院肿瘤中心 张 莉 Contents Contents Contents * * * * * * * 上世纪40年代，化疗方案的出现；90年代，含铂两联方案的确定； * * The types of patients harbouring the mutation are similar between Asian and non-Asian patients. However, it should be noted that mutations are more prevalent in Asian patients. A literature review has shown that the most common activating mutations have a similar distribution between Asian and non-Asian patients.1 This similar distribution of activating mutations suggests that EGFR-TKIs will provide benefits in Asian and non-Asian patients with these mutations. Exon 18-21 encode Ge