基于相似匹配测度的中医证候疗效评价方法研究.pdfVIP

·6· Chinese Journal of Information on TCM Nov.2010 Vol.17 No.11 ·论著 · 基于相似匹配测度的中医证候疗效评价方法研究 孙继佳,陆奕宇,苏式兵 (上海中医药大学,中医复杂系统研究中心,上海 201203) 摘要：目的 提出一种基于相似匹配测度的中医临床证候判别与证候疗效评价方法。方法 结合中药治疗肝炎 肝硬化临床数据资料及其现有证候评判标准,建立肝炎肝硬化“理想证型”,应用相似匹配测度算法进行中医证候的 判别研究,并进行临床疗效评价分析。结果 中药治疗肝炎肝硬化后,每种证候都呈现出一定的变化和分布特点。同 时,进一步通过比较每位患者前后相似匹配测度差值,发现中药用药组疗效优于安慰剂组,但 2 组间差异未见统计学 意义。结论 采用相似匹配测度方法能够从一个新的角度将中医证候分析从定性向定量转化,为中医临床证候研究和 疗效评价提供一定的参考。 关键词：肝炎肝硬化；证候；相似性匹配测度；疗效评价 DOI：10.3969/j.issn.1005-5304.2010.11.003 中图分类号：R228 文献标识码：A 文章编号：1005-5304(2010)11-0006-04 Research on the Assessment of Clinical Therapeutic Effectiveness of TCM Based on Similarity Match Measure SUN Ji-jia, LU Yi-yu, SU Shi-bing (Research Center for Complex System of Traditional Chinese Medicine, Shanghai University of TCM, Shanghai 201203, China) Abstract：Objective To put forward TCM syndrome identification and the assessment of clinical therapeutic effectiveness of TCM syndrome based on similarity match measure. Methods Based on the clinic standard and clinic data, the ideal TCM syndromes of posthepatitic cirrhosis was created. Similarity match measure method was applied to recognize the types of TCM syndromes and assessed the clinical therapeutic effectiveness. Results All TCM syndromes of posthepatitic cirrhosis had some statistical characteristics after treated by Chinese herbal medicine. The therapeutic effectiveness of the Chinese herbal medicine group was better than that of placebo group, but there was no statistical significance between the two groups. Conclusion The application of similarity match measure method would create a new perspective for transform