化瘀通络方治疗寻常型银屑病的临床观察.pdfVIP

· 44。 世界中西医结合杂志2013年第 8卷第 1期 WorldJournalofIntegratedTraditionalandWesternMedicine 2013，Vo1．8，No．1 · 临床 研 究 · 化瘀通络方治疗寻常型银屑病的临床观察 郭建辉 郭雯 【摘要】 观察化瘀通络方治疗寻常型银屑病血瘀证的临床疗效及其对血液流变学指标的影响。 方法 将 120例寻常型银屑病患者随机分为两组。治疗组60例采用口服中药化瘀通络方进行治疗 ， 每日2次；对照组60例采用消银颗粒口服，每次3．5g，每 日3次。两组患者同时外用 10％硫磺软膏， 每日3次。两组均以4周为 1个疗程。两个疗程后依据治疗前后PASI评分判定临床疗效，并检测治 疗组治疗前后血液流变学指标 ，探讨其治疗银屑病的作用机制。结果 两组总有效率分别为 83．33％、56．67％，两组总有效率比较 ，差异有统计学意义 (P0．O1)；治疗组治疗后血液流变学指标 明显改善，与治疗前比较，差异有统计学意义(P0．05)。结论 化瘀通络方治疗寻常型银屑病血瘀 证有较好的临床疗效，且能明显改善血液流变性。 【关键词】化瘀通络方；寻常型银屑病；血液流变学；络病学；血瘀证 【中图分类号】R285．6；R758．63 文【献标识码】A 文【章编号】1673—6613(2013)01一OO44—03 ClinicalObservationofPsoriasisVulgarisTreatedwithHuayuTongluoFormula GUOJian—hui．GUOWen (HebeiCangzhouIntegratedChineseandWesternMedicineHospital，CangzhouHebei061001) A【bstract】 Objective Toobservetheclinicalefficacyonpsoriasisvulgarisofbloodstagnationpat— tern／syndrometreatedwithhuayutongluoformulaandtheimpactsontheindexesofhaemorheology．M ethods Onehundredandtwentycasesofpsoriasisvulgariswererandomizedintotwogroups．Inatreatmentgroup， 60 casesweretreatedwithhuayutongluoformulafororal administration，twiceaday．In acontrolgroup，60 casesweretreatedwithxiaoyingranules．3．5geachtime．threetimesaday．10％ sulfurointmentwasused forthepatientsintwogroupsofrexternalapplication．threetimesaday．Thetreatmentof4weeksmade1ses． sionintwogroups．PASIscorewasevaluatedbeforeandaftertreatmenttodeterminetheclinicalefficaeyafter 2sessionsoftreatment．Theindexesofhaemorheologyweredeterminedbeforeandaftertreatmentinthetreat． mentgrouptoexplorethemechanism onthetreatmentofpsoriasis．Results Thetotaleffectiveratewere 83．33％ and56．67％ intwogroupsrespectively，presentingthestatisticalsignificantdifferenceineompari— son(P0．011．Theindexesofhaemorheologywereimprovedapparentlyaftertreatmentascomparedwith thosebeforetreatmentinthetreatmentgroup，presentingthestatisticalsignificantdifference(P0．05)．