PETMRI多模式分子成像技术新进展.pdfVIP

《现代仪器》 综述与专论 PET/MRI多模式分子成像技术新进展 Advances of a new multimodality molecular imaging technology: PET/MRI 摘  要  近年来，多模式成像技术飞速发展。PET/MRI 作为刚刚走入临床的多模式 分子成像技术组合，成为医学分子影像领域的关注焦点，倍受期待。同机融合PET/ MRI 的出现依赖于PET 和MRI 系统各自的技术革新，以及基于MRI 数据的衰减校 正方法的完善。作为解剖、功能、代谢显像的综合体，PET/MRI 较传统显像手段和 其他成功的多模式成像技术，如PET/CT 和SPECT/CT 有更多、更新的应用优势，并 郑 堃  朱朝晖*  李  方 已积累临床前和初步临床应用的经验。然而，正在走向商品化的PET/MRI 仍有很多 Zheng Kun  Zhu Zhaohui 方面亟待改进和完善，需要通过不断发展、验证才能成为未来辅助临床诊断和指导 Li Fang  治疗决策的有力工具。 关键词  PET/MRI 多模式显像 分子影像 PET/CT 衰减校正 （中国医学科学院 北京协和医学院 北 京协和医院核医学科  北京  100730） Abstract PET/MRI is a rapidly developing multimodality molecular imaging system. Its (Department of Nuclear Medicine, clinical application is an anticipating focus of medical molecular imaging. The development Peking Union Medical College Hos- of PET/MRI depends much on technical innovations of PET and MRI, respectively, as well as pital, Chinese Academy of Medical Sci- improvement of MRI-based attenuation correction method. Through integration of anatomic, ences, Peking Union Medical College, functional, and metabolic imaging, PET/MRI have more advantages over traditional and Beijing 100730) other multi-modality imaging techniques such as PET/CT and SPECT/CT, as demonstrated by the pre-clinical studies and preliminary clinical experiences. However, there is still a long way to go before the full commercialization of PET/MRI, only continuous improvement and innovation can pave its way as a powerful tool for clinical decision-making. Key words PET/MRI Mul