比较分析奥曲肽、垂体后叶素治疗肝硬化上消化道出血的疗效.pdfVIP

论 著 ChniaForeignMed—2ic0a1l4Tre—aNtmOe．n19t—口—固盥_ 比较分析奥曲肽、垂体后叶素治疗肝硬化上消化道 出血的疗效 孙振坤 商丘市第一人民医院分院传染二科 ，河南商丘 476100 摘【要1目的．对比分别应用奥曲肽与垂体后叶素对肝硬化上消化道出血患者进行治疗可以取得的临床疗效。方法 选取该 院近来3年收治的肝硬化上消化道出血患者200例，随机将其分为A、B两组，对比A、B两组患者的临床疗效。结果 A组 患者的总有效率为99％，B组患者的总有效率为70％，A组临床疗效显著优于B组，此外 ，A组患者不良反应发生率为5％， B组患者的不良反应发生率为52％，A组明显低于B组，两者的差异有统计学意义(P0．05)。结论 应用奥曲肽对肝硬化上 消化道出血患者进行治疗 ，其临床疗效明显优于垂体后叶素，并且不良反应出现几率也很低，值得各大医院推广应用。 关【键词】奥曲肽 ；垂体后叶素；肝硬化上消化道出血；临床疗效对比 [中图分类号1R575．2 [文献标识码】A [文章编号】1674—0742(2O14J07(aJ一0021—02 ComparativeAnalysisoftheEffi cacy Between Octreotideand Pituitrin in theTreatmentofLiverCirrhosiswithUpperGastr0intestinalHemorrhage SUN Zhenku TheSecondDepartmentofInfectiousDiseases，ShangqiuFirstPeoplesHospital，Shangqiu，HenanProvince，476100，China [Abstract]ObjectiveTocomparetheclinicalcurativeeffectbetweenoctreotideandpituitrinonlivercirrhosispatientswithupper gastrointestinalbleeding．M ethods200casesoflivercirrhosispatientswithuppergastrointestinalhemorrhageadmittedinourhos— pital inrecent3years wereselectedandrandomlydividedintoA groupandB group，theclinicalefficacyofthetwogroupswas compared．ResultsThetotaleffectiverateofthepatientsinA groupwas99％，andthatofthepatientsinB groupwas70％，the clinicalcurativeeffectofA groupwashigherthanthatofBgroup．Inaddition，theincidenceofadversereactionsofthepatientsin A groupwas5％．andthatofBgroupwas52％．theincidenceofadversereactionsofA groupwassignificantlylowerthanthatof Bgroup，thedifferencebetweenthemwasstatisticalsignificant(只O．05)．ConclusionForpatientswithcirrhosisanduppergas— trointestinalhemorrhage，theclinical curativeeffectofoctreotideisobviouslybetterthanthatofpituitrinwithlowerincidenceof adversereactions，whichisworthyofpopularizationandapplicationinhospita