第6章 细胞的能量转换─线粒体与叶绿体-2010.ppt

MITO time line Pre 1900 First descriptions of mitochondria in cells; speculations about them as bacteria 1930s1930 Formulation of urea and TCA cycle by H. Krebs 1950s1950 Identification of mitochondria by electron microscopy (Palade, Sjostrand) 1950s Mitochondria as site of fatty acid oxidation (Lehninger, Kennedy) Mitochondria as site of respiration and oxidative phosphorylation 1953 Discovery of cytoplasmic inheritance in yeast (Ephrussi, Slonimski) 1955 Definitive respiratory chain analysis (Chance and Williams, Ernster) 1960s 70s1960 Fractionation and characterization of major complexes