先兆子痫患者D一二聚体水平与小时尿蛋白定量的研究()().docVIP

先兆子痫患者D-二聚体水平与24小时尿蛋白定量的研究 中山市博爱医院（中山528403）梅俪凡 【摘要】目的：分析先兆子痫患者D-二聚体水平与24小时尿蛋白定量的相关性。方法：入选的先兆子痫患者82例，运用测定D-二聚体；运用散色比浊法测定24小时尿蛋白定量。利用相关系数（r）来表示 D-二聚体水平与24小时尿蛋白定量的相关性，两组均数之间的比较采用t检验。分析D-二聚体水平与24小时尿蛋白定量的相关性。结果：先兆子痫患者D-二聚体水平与24小时尿蛋白定量呈正相关性。结论：正常孕妇尿中蛋白可轻度增加，这与体位和肾流量加大、肾小球滤过率增加有关。 【关键词】先兆子痫；D-二聚体；24小时尿蛋白定量。 The Research of Preeclampsia D-dimer Levels and 24-hour Urine Protein Mei Li-Van Bo ai Hospital，Zhongshan City（Zhongshan 528403） 【Abstract】Objective：Analysis of D-dimer in patients with preeclampsia and 24 hour levels of urinary protein correlation．Methods：Selected 82 patients with preeclampsia，the use of immune turbidimetric method，D-dimer；the use of casual color Turbidimetric Determination of 24-hour urine protein．Analysis of D-dimer levels and 24-hour urine protein correlation．Using correlation coefficient（r）to represent the D-dimer levels and 24-hour urine protein correlation between the two groups were compared using t test．Results：Preeclampsia D-dimer levels and 24-hour urine protein was positively correlated．Conclusion：Normal pregnancy with the pregnancy of the growthserum D-dimer levels with the increase，indicating that pregnant women in a hypercoagulable state and increased secondary fibrinolysis．Preeclampsia serum D-dimer levels in patients were significantly highersuggesting that these patients is in the coagulation and fibrinolytic state，and there may be chronic DIC．Normal pregnant womenmild increase in urine protein，which increase with body position and the renal flow，glomerular filtration rate．Comprehensive perspective of the two can be more comprehensive grasp of the prognosis and development of eclampsia． 【Keywords】Preeclampsia；D-dimer；24-hour urine protein 妊娠24周左右，在高血压、蛋白尿的基础上出现头痛、眼花、恶心、呕吐、上腹不适等症状者为先兆子痫。它是一种较为复杂的疾病，是妊高症的特殊表现。先兆子痫是子痫的前期，是一种较为复杂的疾病，是严重影响到孕产妇健康，导致母婴发病及死亡的主要原因，影响到5%～8%怀孕女性。我院观察了先兆子痫患者D-二聚体水平与24小时尿蛋白定量的相关性，现将相关结果总结如下 1.材料与方法： 1.1对象：选择2008年11月至2009年11月在我院就诊的先兆子痫患者，符合先兆子痫诊断标准，排除既往有妊娠合并的原发性肾小球肾炎、及其它继发性肾小球肾炎如狼疮性肾炎、糖尿病肾病等疾病的孕妇。共