chapter 21 lipid biosynthesis课件.ppt

Chapter 21 Lipid Biosynthesis 1. Fatty acids; 2. Eicosanoids; 3. Triacylglycerols; 4. Membrane phospholipids; 5. Cholesterol, steroids, and isoprenoids; 1. Fatty acid synthesis takes a different pathway from its degradation Occurs in the cytosol (chloroplasts in plants). Acetyl-CoA provides the first two carbons, which is elongated by sequential addition of two-carbon units donated from malonyl-CoA. Intermediates are attached to the -SH groups of an acyl carrier protein (ACP). NADPH is the reductant. The enzymes are associated as a multi-enzyme complex or even being in one polypeptide ch