调节性 T 细胞与Ⅰ型糖尿病.pdfVIP

调节性 T 细胞与Ⅰ型糖尿病 班级：02级临床3班 姓名：林洁 指导教师：梁静 【摘要】Ⅰ型糖尿病即胰岛素依赖性糖尿病，属于自身免疫性疾病，是由于病毒/细菌感染或遗传因素引起 超敏反应使β 细胞受自身免疫系统攻击而导致功能缺失。近年来发现的调节性 T 细胞在逃避自身免疫、维 持自身耐受方面发挥重要作用，在自身免疫性疾病如Ⅰ型糖尿病研究领域中具有广阔的应用前景。 【关键词】调节性T细胞；免疫调节作用；自身免疫性疾病；Ⅰ型糖尿病 【Abstract 】Type 1 diabetes, which is also called insulin-dependent diabetes ( IDDM ), is an autoimmune disease. It’s due to pancreatic islet β cell destruction caused by the hypersensitivity induced by virus/bacteria infection or genetic factors. Recently, it has been found that regulatory T cell plays an important role in escaping