本文建立了气相色谱法测定牙膏中二甘醇含量的方法用该....docVIP

摘 要 本文建立了气相色谱法测定牙膏中二甘醇含量的方法。用该方法对20个品牌的牙膏进行了测定，并测定了3种宾馆用一次性牙膏和两种牙膏中常用保湿剂原料。牙膏样品用30mL无水乙醇35℃超声提取30min，取上清液用0.45μm有机滤膜过滤后中直接进行气相色谱分析。选用HP-INNOWAX毛细柱，FID检测器，程序升温的方法，外标法定量。二甘醇在10μg/mL~10000μg/mL浓度范围内线性关系良好（r=0.9999）；平均回收率为92.8%(RSD=0.32%，n=9)。结果表明，该方法能有效的分离开几种常用保湿剂，对二甘醇能准确定量，具有操作简单、快速、实用等特点。对我国牙膏等日用化学品中二甘醇的检测提供了理论上的参考，对工厂生产中杜绝二甘醇的出现具有现实的指导意义。 牙膏；二甘醇；保湿剂；气相色谱法 Abstract This paper established a method for the determination of diethylene glycol in toothpaste. The method used for 20 brands of toothpaste were determined and measured three kinds of one-time toothpaste and guesthouse with two toothpaste raw materials used in moisturizing agents. The sample was extracted with 30 mL anhydrous ethanol in 35 ℃ ultrasound 30 min. After being filtrated with a 0.45 μ m organic membrane filters, the extract was determined by GC directly. An HP-INNOWAX capillary column was employed for separation. We choose FID detector, temperature-programmed way. And external standard method was used for quantification. Good linear relationship was maintained over the range of 10 μ g / mL ~ 10000 μ g / mL (r = 0.9999). Average recovery rate was 92.8% (RSD = 0.32%, n = 9). The results showed that this method can effectively leave the sub-Several moisturizing agents, the diethylene glycol can be accurate quantitative. The method is simple, fast and practical. This method provide a theory of reference for Chinas toothpaste Dengri chemicals in the detection of diethylene glycol to and a practical guidance to prevent the emergence diethylene glycol in factory production . Key words: toothpaste; diethylene glycol; moisture; GC 目 录1 引言…………………………………………………………………1 1.1 研究本课题的目的和意义………………………………………1 1.2二甘醇及常用保湿剂背景……………………………………2 1.3 二甘醇含量测定方法的研究现状…………………………………3 1.4 气相色谱的简介及原理 ………………………………………… 1.5 气谱色谱的应用…………………………………………………… 2 材料与方法……………………………………………………… 2.1 实验材料………………………………………………………… 2.2 实验仪器…………………………………………………………… 2.3 色谱分析条件……………………………………………………… 2.4 实验方法……………………………………………………………