宁波市第二医院住院患者产ESBLs大肠埃希菌耐药性及基因型研究.pdfVIP

宁波市第二医院住院患者产 ESBLs大肠埃希茵耐药性及基 因型研究 陈梦婷张顺蔡挺 【摘要】 分别为85．33％(64株)、81．33％(61株)、49．33％(37株)、10 情况较严重；ESBLs基因型以CT×一M一14最常见。 【关键词】 大肠埃希菌超广谱D一内酰胺酶耐药性基因型 resistanceand of JE奢c^eric，，jacofjisoIatedfrom in Second Drug genotypeESBLs—producing patientsNingbo HospitaIC删^dengf加g， ZHANG Schoolof 31 Shun．CAlTing．MedicaINingboUniversity．Ningbo5000．Chlna To the resistance 【Abst旧ct】 and of Objectiveinvestigatedrug genotypesextended—spectrum Escnerfcn妇cof，isolatedfrom in Second MethodsC|inicalstrainsofE§cher』ch妇co／j BLs)一producing patients Ningbo HospitaI． wereisOlatedfrOm Of Second December2013and 201 resistancewas jnpatientsNingbO HOspitaIduring May4。Drug detected and OfESBLswasdeterminedPCRmethOd．ResuItsAl|75cIinicalis0IatesOfEscher『cn『ac0／fwereresislanttO genOtype by shOwedresistancerate and ampiciIIin，andhigh Of廿1；rd—generationcephalOspOrins，fIuOroquinoIonespOsi— tiVeratesOf TEM，CT×一M一9 were ESBLs—prOducjnggenotypes group，CT×一M一1grOup，O×A一1group，SHV，O×A一10group 8533％(64)，8133％(61)，49 of64isoIa{eswithTEM 33％(37)，10．67％(8)，5．33％(4)and4．00％(3)，respectiveIy．Thegenotype wasTEM一1．Themain ofCT×一M wereCT×一M一14and account gene genotypes group CT×一M一55，whichfor andCT×一M一79 29．33％(22)，respectivefy：whileCT×一M一3，CT×一M一15，CT×一M一24，CT×一M一27，CT×一M一65，CT×一M一69geno— accOuntedforfewer ofCT×一M of8isOlateswith0×A一1 was 0f4 types percentage genotype．Thegenotype