中心性浆液性脉络膜视网膜病变的光学相干断层与视力的相关性研究.doc

中心性浆液性脉络膜视网膜病变的光学相干断层扫描与视力的相关性研究 张文娟 王志涛 孙坚 刘恒明 孙旭芳 通讯作者 孙旭芳 The correlation of Visual Acuity with Optical Coherence Tomography in Central Serous Chorioretinopathy Zhang Wenjuan, Wang Zhitao, SunJian, Liu Hengming, Sun Xufang Department of Ophthalmology, Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China 【摘要】 目的 探讨频域光学相干断层扫描（SD-OCT）在中心性浆液性脉络膜视网膜病变（CSC）中的应用并对CSC浆液性脱离区各项定量指标的测量结果与患者视力的关系进行分析。 设计 回顾性病例研究 对象 2010年11月至2011年3月因视力减退、视物变形在我院就诊并确诊为CSC的34例（37只眼）（男30，女4，平均年龄42.6岁，年龄跨度为19-58岁）。 方法 所有患者均应用Spectralis OCT(Heidelberg Engineering, Dossenheim, Germany)进行检查，观察视网膜浆液性脱离区形态学特征并根据不同形态进行视力分析，进一步9个分区视网膜厚度及体积，然后手工测量脱离的高度(DH)采用SPSS1.0软件9个分区视网膜厚度及体积；浆液性脱离区脱离的高度(DH)鉴别的进行定量的追踪观察）Abstract】 Objective To investigate the clinical application of spectral domain-optical coherence tomography (SD-OCT) in the central serous chorioretinophthy (CSC) and to analyze the relation between the visual acuity and measurements of the serous detachment of CSC. Design Retrospective case study. Object Thirty-seven eyes of 34 patients (30 men, 4 women; mean age 42.6 years; range19-58) diagnosed with CSC in our hospital between Nov. 2010 and March 2011. Methods All patients were examined with Spectralis OCT (Heidelberg Engineering, Dossenheim, Germany) .To observe retinal morphological features and to measure 1mm,3mm,6mm(9 partitions) macular retinal thickness and volume with macular topographic map analysis software, then to measure the serous detachment height (DH) and detachment width (DW) manually. Finally, we use SPSS17.0 software to analyze the correlation among the vision with values. Main outcome measures 1mm,3mm,6mm(9 partitions) macular retinal thickness and volume; the serous detachment height (DH) and detachment width (DW); Visual acuity. Results 1. Images from SD - OCT show us: the pure nerve layer detachment,22 eyes; the pure retinal pigment epithelium detachment(PED), 0 eye; nerve layer detachment merged with PED,13 eyes;