ENVR 133 Bacterial Pathogens - Overview.ppt

ENVR 133 Bacterial Pathogens - Overview Mark D. Sobsey Typical Procaryotic Cell Gram Negative Outer Cell Membrane and Lipopolysaccharide Structure Structure of a Gram-Negative Cell Wall Porins Porins are structures in the outer membranes of Gram-negative bacteria They allow diffusion of low molecular weight compounds into the periplasmic space. Function as channels for small hydrophilic molecules. Porins are beta-barrel proteins in the outer membranes. Porins occur as trimers in the membrane. In E. coli, porins with different specificities exist, e.g.. maltoporin and phosphoporin. Shigello