14例肺原发性粘膜相关淋巴组织淋巴瘤疗效分析.pdfVIP

第八届中国老年肿瘤学大会年会论文集 14 例肺原发性粘膜相关淋巴组织淋巴瘤疗效分析 房辉，李晔雄，宋永文，王维虎，金晶，任骅，王淑莲，刘跃平 作者单位：100021 中国医学科学院肿瘤医院 放疗科 Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, P.R. China 通讯作者：李晔雄 【摘要】 目的：分析肺原发性粘膜相关淋巴组织淋巴瘤的临床特征和预后。方法：回顾性分析 14 例肺原发性粘膜相关淋巴组织淋巴瘤患者，其中 I 期 8 例，II 期 5 例，III 期 1 例。4 例接受手术治 疗，5 例手术加放疗或化疗，3 例化疗加放疗，2 例单纯化疗。结果：中位年龄为 55 岁，男女之比 为 1:1.33。中位随访时间为48.3 个月。全组患者均存活，3 例患者出现治疗失败。全组患者的 2 年 和 4 年的无进展生存率分别为 90.9%和 69.3% 。治疗失败发生在疗后25-37 个月，失败部位为双肺、 纵隔淋巴结、右肺和脑膜。结论：肺原发粘膜相关淋巴组织淋巴瘤为惰性淋巴瘤，预后良好。临床 上可根据患者病变范围和身体状况选择适当治疗。 【关键词】肺原发性粘膜相关淋巴组织淋巴瘤；临床特征；治疗；无进展生存率；总生存率 Clinical Characteristics and Treatment Outcome of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma FANG Hui, LI Ye-xiong, SONG Yong-wen, WANG Wei-hu, JIN Jing, REN Hua,WANG Shu-lian, LIU Yue-ping. Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, P.R. China Corresponding author: LI Ye-xiong 【Abstract 】Objective: To analyze the clinical features and prognosis of patients with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma. Methods: This retrospective study included 14 patients with pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma between 1999 and 2012. Eight patients (57.1% ) had Ann Arbor stage IE disease, 5 (35.7%) stage IIE and 1 (7.1%) stage IIIE disease. Overall, patients were treated with surgery alone (n=4), surgery plus radiotherapy or chemotherapy (n=5), chemotherapy plus radiotherapy (n=3), or chemotherapy alone (n=2). Results: The median age at diagnosis was 55 years. The ratio of male to female was 1:1.33. With a