成年人肺结核患者T淋巴细胞亚群_自然杀伤细胞及免疫球蛋白的检测与分析.pdfVIP

2003 3 6 CHINA TR PICAL MEDICINE Vol13 No16 November 2003 767 [] T 周世明 贾 杰 杨建国 摘要 目的 探讨老年人与青壮年人肺结核患者的免疫功能的特点, 指导临床治疗 方法 93 例活动性肺 结核病人,按年龄分为青壮年组和老年组应用流式细胞术检测33 例老年人肺结核60 例青壮年肺结核的T 淋巴细 胞亚群自然杀伤细胞,比浊法检测其血清免疫球蛋白, 并检测20 例正常人T 淋巴细胞亚群自然杀伤细胞作为对照 组 结果 老年人肺结核与青壮年人比, CD CD PCD 比值下降与CD CD 上升差异均有显著性( P 0101) ,与对 4 4 8 8 56 照组比,CD 与CD 上升CDPCD 比值下降差异均有显著性( P 0101) , 血清IgGIgMIgA 水平改变差异无显著性( P 8 56 4 8 0105) 结论 老年人肺结核细胞免疫功能低下, 体液免疫无明显变化 关键词 肺; 结核;免疫; 老年人; 青年人1 中图分类号:R521 文献标识码:A 文章编号: 1009- 9727(2003)06- 0767- 02 Detection and comparison of T- lymphocyte subsets, NK- cell and immunoglobulin in pulmonary tuberculosis pa- tients1ZH U Shi-ming,JIA Jie,YANG Jian-guo, Department of infectious Diseases of Hainan Provincial People. s Hospital,Haikou 570311,Hainan,P1 R1 China1 Abstract Objective To explore the immune funcition of the aged and young adult pulmonary tuberculosis patients and provide guidancefor clinical treatment1 Methods Thirty- three senile and 60 young pulmonary tuberculosis patients were selected as the ( 上接第766 页) 1 Table 1 Comparison of results in treatment of dermatophytoses in the two groups ( %) (%) Group Illness No1 case No1 cured Effective Improved No effect Rate of cure Total effective rate Tinea corporis 78 70 4 2 2 891 7 9419 Tinea cruris 174 153 13 3 5