产ESBLs和AmpC酶阴沟肠杆菌的检出率及耐药性监测.pdfVIP

1808 Chin J Lab Diagn, November, 20 10, Vol 14, No . 11 : 1007- 4287 ( 2010) 11- 1808- 03 ESBLs AmpC 1 2 1 1 1 邵良荣, 邵 杰 , 居会祥 , 孙明中, 陈思聪 ( 1. , 224001; 2. , 210046) : ESBLs AmpC 2005 1 - 2007 1 , ESBLs AmpC 81 , 29 ESBLs, 35 . 0% ; 3 1 AmpC , 38. 3% ; 14 , 17. 3% / 3% , 1 2% , ESBLsAmpC / , AmpC ESBLs , ESBLs : ; ; AmpC ; : R4465 : A The Detection Ratio and Drug Resistance of Enterobacter Cloacae Producing ExtendedSpectrum lactamases and AmpC Enzyme SHAO Liangrong, SHAO Jie, J UHuixiang , et al. (Aff iliated Yancheng Hosp ital ; Medical College of Southeast Uni ersity , Yancheng, Jiangsu 224001, China) Abstract: Ob ective To s udy on he de ec ion ra io and drug resis ance of en erobac er cloacae producing ex endedspec rum lac amases ( ESBLs) and AmpC Enzyme. Methods The de ec ion ra io and drug resis ance of en erobac er cloacae producing ES BLs and AmpC Enzymein w ere analysed, and so w ere hose confirmed cases w i h en erobac er cloacae infec ion, during J anuary 2005 o J anuary 2007 in our hospi al . Results Among 81s rains of En erobac er cloacae, 29 s rains producedESBLS, and he de ec ion ra io was abou 35 . 0% ; 31 s rains produced AmpC Enzyme, w i h he de ec ion ra io abou 38. 3% ; and 14 s rains produced bo h ESBLs and AmpC Enzyme, w i h he de ec ion ra io abou 17. 3% . The drug resis ance of compound agen s of enzyme inhibi ors like cefoperazone/ sulbac amw as 3% , whileforimipenemandmeropenemwere 1% and 2% , respec ively. Conclusion En erobac ercloacaeisone of he Common Nosocomial Pa hogens .The Amp CEnzyme, ESBLs produc ion have become he wo main f ac ors leading he drug resis