中西医结合治疗妊娠期外阴阴道假丝酵母菌病临床观察.pdfVIP

世界中西医结合杂志2012年第7卷第6期 WorldJournalofIntegratedTraditionalandWesternMedicine 2012，Vo1．7，No．6 ·497 · · 临床 研 究 · 中西医结合治疗妊娠期外阴阴道假丝 酵母菌病临床观察 高丽霞 吉广庆 【摘要】 目的 观察中西药结合治疗妊娠期外阴阴道假丝酵母菌病的临床疗效。方法 96例 患者随机分成两组。治疗组48例，中药局部用药加克霉唑栓阴道上药。对照组48例，2％碳酸氢钠 局部用药加克霉唑栓阴道上药，7d为 1疗程，连用2个疗程。观察比较两组疗效和治愈者 1个月后 的复发率。结果 治疗效果和复发率两组比较差异均有统计学意义。治疗组总有效率达97．9％，治 愈后复发率仅2．7％，对照组总有效率达89．6％。治愈后复发率 15．6％。两组临床表现改善情况与 治疗前比较，差异有统计学意义，且治疗组疗效显著优于对照组。两组真菌检测率，远期真菌检测优 于近期疗效，治疗组优于对照组 ，差异有统计学意义。结论 中西医结合治疗妊娠期外阴阴道假丝酵 母菌病，症状改善明显，复发少，值得临床推广。 【关键词】 中西药结合 ；妊娠期；假丝酵母菌病 【中图分类号】R711．31 【文献标识码】A 【文章编号】1673—6613(2012)06—0497—03 ClinicalObservation ofVulvovaginalCandidiasisin Pregnancy Treated with IntegratedChineseandW esternM edicine GAOLi—xia ．JiGuang—qing~ (1．AffiliatedHospitalofShanxiCollegeofTraditionalChineseMedicine，TaiyuanShanxi030024；2．Shanxi CollegeofTraditionalChineseMedicine，TaiyuanShanxi030024) A【bstract】 Objective Toobservetheclinicalefficacyofvulvovaginalcandidiasis(VVC)inpreg— nancytreatedwith integratedChineseandwesternmedicine．M ethods 96 caseswererandomizedintotwo groups．48casesinatreatmentrgoupweretreatedwithChinesetopicalmedicineandclotrinazolevaginalsup— positories．48casesinacontrolrgoupweretreatedwith2％ topicalsodium bicarbonateandclotrinazolevagi— nalsuppositories．7一daytreatmentmade1session．Thecontinuous2sessionsoftreatmentwererequired．The efficacyandtherecurrencerateofthecurativecasesin 1monthwereobservedandcomparedbetweentwo rgoups．Results Thetherapeuticeffectandrecurrencerateweredifferentsignificantlyinstatisticsbetween tworgoups．Inthetreatmentrgoup．thetotaleffectiveratewas97．9％ andtherecurrenceratewasonly2． 7％ ．Inthecontrolgroup．thetotal effectiveratewas89．6％ andtherecurrenceratewas15．6％ ．Theim— provementsintheclinicalmanifestationsaftertreatmentweredifferentsignificantlyinstatisticsascompared withthosebeforetreatmentineithergroup．Theefficacyinthetreatmentgroupwassuperi