Currentstatusoftreatmentcompletionandfatality…：完成治疗和死亡的现状….pdfVIP

INT J TUBERC LUNG DIS 8(4):458–464 © 2004 IUATLD Current status of treatment completion and fatality among tuberculosis patients in Spain † ‡ J. A. Caylà,* J. A Caminero, R. Rey, N. Lara,* X. Vallés,* H. Galdós-Tangüis,* Working Group on Completion of Tuberculosis Treatment in Spain * Tuberculosis Investigation Unit of Barcelona, Servicio de Epidemiología, Agencia de Salud Pública, Barcelona, † Hospital General Universitario de Gran Canaria ‘Dr Negrín’, Las Palmas de Gran Canaria, ‡ Instituto de Salud Carlos III, Madrid, Spain S U M M A R Y OBJECTIVES: To determine treatment completion among 2.59–13.89) and immigration (OR 8.57, 95%CI 3.78– patients with tuberculosis (TB), and to analyse factors 19.45); sex, age, homelessness, incarceration, directly associated with treatment default and fatality. observed treatment (DOT) or hospitalisation were not METHODS: A prospective cohort study of patients who associated with default. Variables found to be predictive began treatment between 1 June 1999 and 31 May 2000 of fatality were alcoholism (OR 6.38, 95%CI 2.09– in areas where members of the SEPAR Tuberculosis and 19.48), human immunodeficiency virus (HIV) infection Respiratory Infections Group work. Factors associated (OR 7.08, 95%CI 2.08–29.15) and age 64 years (OR with treatment default and fatality were studied using 10, 95%CI 2.9–34.07), whereas sex, IVDU, homeless- logistic regression, calculating odds ratios (OR) and their ness, DOT and hospitalisation were not. 95% confidence intervals (95%CI). CONCLUSIONS: In industrialised countries, IVDU patients RESULTS: The study involved 142 physicians f