TheroleofvitaminDinprotectingtype1diabetesmellitus-：维生素D的保护1型糖尿病中的作用—.pdfVIP

DIABETES/METABOLISM RESEARCH AND REVIEWS REVIEW ARTICLE Diabetes Metab Res Rev 2005; 21: 338–346. Published online 26 April 2005 in Wiley InterScience (). DOI: 10.1002/dmrr.557 The role of vitamin D in protecting type 1 diabetes mellitus 1 Khanh vinh quoc Luong * Summary Lan Thi Hoang Nguyen1 Dung Ngoc Pham Nguyen1,2 The relationship between autoimmune diabetes or type 1 diabetes mellitus and vitamin D has been reported in the literature. Many factors, environmental 1Vietnamese American Medical and genetic, have been known, as risk factors, to cause both type 1 diabetes Research Foundation, Westminster, and vitamin D deficiency. Vitamin D treatment has improved or prevented California type 1 diabetes mellitus in animals and humans. Vitamin D also has been 2Metropolitan State Hospital, known to protect from autoimmune diseases in animal models. Therefore, Norwalk, California it would be interesting to review the role of vitamin D in type 1 diabetes mellitus. Copyright  2005 John Wiley Sons, Ltd. *Correspondence to: Khanh vinh quoc Luong, 14971 Brookhurst Street, Westminster, CA. 92683, Keywords vitamin D; diabetes mellitus; 1,25-dihydroxyvitamin D3 USA. E-mail: Lng2687765@ Introduction Vitamin D has been known as a regulator of bone and mineral metabolism by regulation of calcium absorption in the gut and reabsorption by the kidney. In addition, 1,25-dihydroxyvitamin D [1,25(OH) D ] is also recognized in the