TheTreatmentofVascularDementia：血管性痴呆的治疗.pdfVIP

4 The Treatment of Vascular Dementia in Acupuncture Based on Syndromes Differentiation 1,2 1 1 2 Liangdeng Zhang , Jie Wang , Kuiwu Yao and Ji Zhang 1Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 2School of Acupuncture and Moxibustion, Beijing University of Chinese Medicine, Beijing China 1. Introduction Vascular dementia (VaD) is a progressive neurodegenerative syndrome that encompasses a wide spectrum of cognitive disorders caused by cerebrovascular diseases (Pennisi et al., 2011; Selnes Vinters, 2006). VaD and Alzheimers disease (AD) are the most common dementia syndromes in the elderly (Matioli Caramelli, 2010). However, only a small percentage of elderly patients have ‘pure AD’ or ‘pure VaD’ (Fotuhi et al., 2009), both of which are caused by mixed aetiology and pathophysiology. Clinical diagnostic criteria of VaD show moderate sensitivity (50-70%) and variable specificity (64-98%) (Jellinger, 2008). The frequency of specific neuropathologic features of vascular cognitive impairment depends largely on study exclusion criteria (Selnes Vinters, 2006). Although the use of voxel-based multivariate analysis in 18FDG PET extracted a metabolic pattern could differentiate VaD and AD efficiently (Kerrouche et al., 2006). VaD is in sile