柴胡黄芩配伍不同提取部位对大鼠急性酒精性肝损伤肝组织中环氧合酶_2表达的影响.pdfVIP

Effects of D SF on the NO Sy stem L evel in Exper im en ta l Ra ts of M yocard ia l Ischem ia 1 2 3 4 TAN Ru i , GU J ian , L IU Ru , LON G ShaoJ iang ( 1 D ep artm ent of B ioengineering, Sou thwe st J iaotong U n iversity, Chengdu 6 10051, Ch ina; 2 In stitute ofM inority M edicine, Sou th west U n iversity for N ationalitie s, Chengdu 6 1004 1, Ch ina; 3 College of L ife Science and Techno logy, Southwest U n iversity for N a tionalitie s, Chengdu 6 1004 1, Ch ina; 4 Chengdu U n iversity of Traditional Ch inese M edicine, Chengdu 6 10075, Ch ina) A b stract　Objective: To ob serve the effect of D SF on NO System in exp erim ental m yocardial ischem ia model by ligating the cor nary de scending branch M ethod s: W istar m ice were divided into control group , model group , D an shen group and D SF group to ob serve the effect of D SF on variation s of the NO system R e su lts: Comp ared w ith model group , conten t of NO , NO S and cNO S in serum and m u scle in D SF group were sign ificantly increa sed ( P 005或 P 001) Bu t there was no statisical difference on the con tent of iNO S ( P 005) comp ared w ith model group The exp re ssion of cNO S mRNA wa s increased ( P 005) Conclu sion: The m echa n ism of D SF in treating coronary is realized by imp roving the con ten t ofNO , the activity ofNO S and exp re ssion of cNO S mRNA in myo cardial tissue Key words　M yocardialischem iamodel; NO; NO S; cNO S mRNA 柴胡黄芩配伍不同提取部位对大鼠急性酒精性 肝损伤肝组织中环氧合酶 2表达的影响 王宪龄 ,宋 　宁 ( ) 河南中医学院 ,河南郑州 450008 　　摘要 　目的:研究柴胡黄芩配伍不同提取部位对大鼠急性酒精性肝损伤肝组织中环氧合酶 2 表达的影响 。方 法 :采用白酒灌胃造成大鼠急性酒精性肝损伤模型 , 以当飞利肝