重组人血管内抑制素微量输液泵持续输注治疗恶性肿瘤临床疗效观察.pdfVIP

20 11 15 1 Jou nal of Clinical M edicine in P act ice ∀39 ∀ 曾建伦, 彭济勇, 江 亮, 汤江林, 李 艳, 鲁志兵, 占志强, 徐新颜, 朱泽文, 温莹浩 ( , , 337000) : ( ) 37 2 ( n = 16) : , 135 mg, 3 ( 360 h) , 21 d ( n = 21) : , 15 mg, 500 mL , 1~ 14 , 7 ; , 21 1 1 , 2 ( P 0.01) ; 2 , : / ; ; ; : R 730. 5 : A : 2011) Therapentic effect of endostar durative transfusion combined with chemotherapy on kinds of advanced malignancies ZENGJianlun, PENGJiyong, JI NG Liang, T NGJianglin, LI Yan, LU Zhibing, ZH N Zhiqiang, XU Xinyan, ZHU Zewen, WEN Yinhao ( Dep ar tment of Oncology , P ingx iang P eop le!s H osp ital , P ingx iang , JiangX i, 337000) BSTR CT: Objective T o obse ve p ospect ively and syst em at ically t he efficacy and safety of hendost at in inject ion( YH16, Endosta ) du at ive t ansf usion combined w ith t he chemot he apy on kinds of advanced malignancies. Methods Endost a combined w it h chemothe apy w e e adminis t at ed to 37 malignant cases of St age ~ conf i med by histopathology o cytopat hology . T he 37 pat ient s we e andomly divided int o tw o g oups: expe iment al g oup ( n = 16) t eat ed wit h endosta du at ive t ansf usion combined w it h chemot he apy: 135 mg endosta was solved in 3 minit ansfe pump w as administ e ed by cont inuous infusion f o 360 hou s and epeat ed aft e 21 days late . Con t ol g oup ( n = 21) , t eat ed w it h endost a combined w it h chemot he apy, w as confi med by histopathology o cytopathology. 15 mg endost a solved in 500 mL of no mal saline w as slow 21int avenously d opped f om day 1 t o day 14 and epeat ed 7 days lat e .