功能磁共振成像评价帕金森病康复干预：有意义神经保护策略.docVIP

功能磁共振成像评价帕金森病康复干预：有意义的神经保护策略 帕金森病是一种进行性神经退行性疾病，影响全世界大约有10万人口。在临床应用中，功能成像在鉴别原发性帕金森病和非典型震颤(性)麻痹上的作用是有限的。想要针对帕金森病患者制定个性化的康复策略，就需要考虑到运动和非运动症状、精神身体状态、物质环境和社会环境的发展，这几项因素将在接下来的几年里引发人们的极大研究兴趣。 意大利罗马生技医疗大学的Carlo Augusto Mallio博士认为，定量功能性磁共振成像将在评估临床试验中康复治疗的有效性，及其对多巴胺神经元的病理变化和其代偿机制方向起着至关重要的作用。相关内容发表在2015年5月第5期《中国神经再生研究（英文版）》杂志上。 Article: Evaluating rehabilitation interventions in Parkinson’s disease with functional MRI: a promising neuroprotective strategy by Carlo Augusto Mallio, Bruno Beomonte Zobel, Carlo Cosimo Quattrocchi (Departmental Faculty of Medicine and Surgery, Unit of Diagnostic Imaging, Università Campus Bio-Medico di Roma, Rome, Italy) Mallio CA, Zobel BB, Quattrocchi CC (2015) Evaluating rehabilitation interventions in Parkinson’s disease with functional MRI: a promising neuroprotective strategy. Neural Regen Res 10(5):702-703. 欲获更多资讯：请与《》联络；联络电话：，或用电子邮件联络：eic@。/ Evaluating rehabilitation interventions in Parkinson’s disease with functional MRI: a promising neuroprotective strategy Parkinson’s disease is a progressive neurodegenerative disorder affecting approximately 10 million people worldwide. The role of structural imaging in Parkinson’s disease is limited to support clinical findings in differentiating idiopathic Parkinson’s disease from atypical or secondary parkinsonisms. Dr. Carlo Augusto Mallio (Università Campus Bio-Medico di Roma, Rome, Italy) considered that quantitative functional magnetic resonance imaging will play a crucial role to measure effectiveness of rehabilitation therapies in clinical trials and their effect on the dopaminergic pathological stream and its compensatory mechanisms. The relevant study has been published in the Neural Regeneration Research (Vol. 10, No. 5, 2015). Article: Evaluating rehabilitation interventions in Parkinson’s disease with functional MRI: a promising neuroprotective strategy by Carlo Augusto Mallio, Bruno Beomonte Zobel, Carlo Cosimo Quattrocchi (Departmental Faculty of Medicine and Surgery, Unit of Diagnosti