沙利度胺对血液肿瘤患者致栓作用的初步探究.pdfVIP

# 124# Ch inese ourn al ofTh rom bosis and H em ostasis 2010 Vol 16 No 3 * , , (, , 2000 11) : 30 - 1 A-140Õ D-- 1A - 2 , - 1 D-( P 0. 05P 0. 0 1), (P 0. 05), , : ; ; [] R 733 [] A [] 1009- 62 13( 2010) 03-124-03 Prelim inary Inquiry ofThalidomide on Thrombosis Function in Patientswith HematologicTumors W ANG-L ei, HU un-pe,i Y E W e-i de , ( Departm ent ofH em atology, Shanghai N inth P eop le s H osp ita,l M ed ical College, Shanghai iao T ong Un iversity, Shanghai, 200011, Ch ina) Abstract: Objective T o inquiry of thalidom ide on throm bosis function in patients w ith hem atolog ic tum ors. M ethods W e evaluated m akers of haem ostatic function, including serum levels of endothelin- 1, throm bom odu lin, p latelet A-granu lem em brane protein- 140, fibrinogen and its degradation products D-d mi er as w ell as activ ities of coagu lation factorsÕ, antithrom bin, tissue plasm inogen activator, plasm inogen activa- tor inhibitor and A - p lasm in inh ib itor, during treatm ent w ith thalidom ide in 30 patients w ith hem atolog ic 2 t