《A brief review of recent advances in stem cell biology》.pdfVIP

NEURAL REGENERATION RESEARCH April 2014,Volume 9,Issue 7 SPECIAL ISSUE A brief review of recent advances in stem cell biology 1 2 3 Jinhui Chen , Libing Zhou , Su-yue Pan 1 Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN, USA 2 Guangdong-Hongkong-Macau Institute of CNS Regeneration (GHMICR), Jinan University, Guangzhou, Guangdong Province, China 3 Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China Abstract Corresponding author: Stem cells have the remarkable potential to develop into many different cell types, essentially with- Jinhui Chen, M.D., Ph.D., Stark out limit to replenish other cells as long as the person or animal is still alive, offering immense Neuroscience Research Institute, hope of curing Alzheimer’s disease, repairing damaged spinal cords, treating kidney, liver and lung Department of Neurological Surgery, diseases and making damaged hearts whole. Until recently, scientists primarily worked with two Indiana University School of Medicine, kinds of stem cells from animals and humans: embryonic stem cells and non-embryonic “somatic” 980 W. Walnut Street, Indianapolis, IN or “adult” stem cells. Recent breakthrough make it possible to convert or “reprogram” specialized 46202, USA, Chen204@. adult cells to assume a stem stem-like cells with different technologies. The review will briefly dis- cuss the recent progresses in this area. doi: 10.4103/1673-5374.131565 / Key Words: stem cell; adult stem cell; embryonic stem cell; somatic cell nuclear transfer; induced pl