《A Novel Hydrolytic Product from Flesh of Mactra veneriformis and Its Bioactivities in Calcium Supplement》.pdfVIP
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andCoastalSea
J-Ocean Researchl
Univ.China(Oceanic
DOI10.1007/s11802.012—1960—4
ISSN
1672—5182,201211(3):389-396
http.//www.ouc.edu.cn/xbywb/
E-mail:xbywb@012C.edu.cn
andItsBioactivitiesinCalcium
Supplement
WANG WUHa01)’2)’+
Ruil),孙,and
Lingchon91),∞,CHENShiyongn,LIU
21 R.China
0046,P
Science,NanjingUniversityofChineseMedicine,Nanjing
1)CollegeofPharmaceutical
First-Class TraditionalChineseMedicine Medicine,
2)National Disciplinefor ofNanjingUniversityofChinese
Key
RChina
210046,P
Nanjing
March June
8,2012:revised
(Received April26,2012;accepted3,2012)
2
@Ocean ofChina.SciencePressand Berlin 201
University Springer-VerlagHeidelberg
AbstractTo fleshresidueofMactra was toenzymatic
preparecalcium.bindingpeptides,the Veneriformissubjected hydrolysis.
ofthe wasconfirmedtobethemostsuitable for
the of calcium enzyme
Bycomparingcapabilitycombining hydrolyzates,pepsin
thefleshresiduetorelease theseventested
among proteases.Thepepsin
hydrolyzing calcium—bindingpeptides
wasdividedintothreefractions tothemoleculeofits from0.5to15kDa.The
according weight composition.whichranged
fractionnamedPHM
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