雷贝拉唑联合莫沙必利治疗返流性食管炎疗效观察.pdf

2009 11 30 ( 11) SichuanM edicalJournal, 2009, Vo.l 30, o. 11 1747 论著 刘黎霞 (, 61007 1) 观察雷贝拉唑联合莫沙必利治疗返流性食管炎的临床疗效 68例返流性食管炎患 采用 随机方法分成两组, 每组 34例; 组应用雷贝拉唑联合枸橼酸莫沙必利; 组单用雷贝拉唑, 评价其临床疗效 68例返流性食管炎患 完成 4周治疗, 组组症状缓解总有效率分别为 941% ( 32 /34), 706% ( 24 /34) ; 组总有 效率优于组 (P 005) 内镜下缓解情况, 组组有效率分别为 90% ( 18/20)533% ( 8/ 15); 组有效率优于 组(P 005) 雷贝拉唑联合枸橼酸莫沙必利治疗返流性食管炎临床改善迅速, 临床疗效优于单用雷贝拉唑 返流性食管炎; 雷贝拉唑; 莫沙必利 R 57 1 A 1004-0501( 2009) 11-1747-02 Observation on therapeutic effect of rabeprazole andm osapride curing reflux esophagitis. LIUL i-x ia. CaotangH osp i- tal, ThePeop lesH osp ital of Sichuan, Chengdu, Sichuan 6 10071, China Abstract Objective T o observ tion the effic cy of r bepr zole nd mos pride in the tre tm ent of reflux esoph gitis ( RE). M ethods 68 c ses of RE w s r ndom ized to 2 groups: group , group w ith 34 c ses in e ch group. Groups w ere tre ted w ith r bepr zole nd m os pride; groups were tre ted w ith r bepr zole single. R esults 68 c ses of RE w ere tre ted for 4 weeks. The tot l effective r te w ere 941% ( 32 /34) , 706% ( 24 /34). G roup w s higher th n group (P 005). The he ling r te of esoph ge lm ucos l lesion in group w s h igher th n th t of group (P 005). Conclusion The effic cy of r bepr zole nd mos pride in the tre tm ent of RE is better th n th t of r bepr zole single. Key words reflux esoph gitis; r bepr zole; mos pride , , : 18 ~ 70 ; , 192% [ 1] , , 6 , (= + ); 1 (): 0; 1, , 2005 6~ 2008 4 68 ; 2, , ; 3, , : 0 ; 1, 3; 2 , 4 ~ 6 ; 3 , 7