妇科恶性肿瘤保留生育功能：希望抑或陷阱.pdfVIP

中华临床医师杂志( 电子版)2015 年1 月第9 卷第1 期 Chin J Clinicians(Electronic Edition),January 1,2015,Vol.9,No.1 ·45 · ·专题综述· 妇科恶性肿瘤保留生育功能：希望抑或陷阱 周彬 张师前 【摘要】 妇科恶性肿瘤逐年呈年轻化趋势，这部分患者保留生育功能的治疗近年来引起了妇 产科专家的关注。本文简述了子宫颈、子宫内膜以及卵巢恶性肿瘤患者保留生育功能治疗的指征、 方法及预后，评价了妇科恶性肿瘤保留生育功能治疗对患者生育力的影响，介绍了生殖医学技术尤 其是冷冻技术的发展对于妇科恶性肿瘤保留生育功能治疗的助力，权衡了患者的获益及风险。分析 认为，妇科恶性肿瘤患者保留生育功能治疗既给患者带来了希望，又为临床诊疗布下了陷阱，妇科 恶性肿瘤保留生育功能治疗需多学科协作、全面评估病情，鼓励患者参与多中心临床研究，将是未 来的研究方向。 【关键词】 妇科恶性肿瘤； 保留生育功能 Conservative treatment for gynecologic tumors: hope or trap Zhou Bin, Zhang Shiqian. Department of Reproductive and Genetic Science, Taian Central Hospital, Taian 271000, China Corresponding author: Zhang Shiqian, Email: r370112@126.com 【Abstract 】 More and more women in their reproductive age of group suffer from gynecologic tumors. This has aroused much interest in recent years. This review aimed to address the general situation of gynecologic tumors and also retrospect the reproductive outcome of the patients who were treated with the conservative therapy. The development of reproductive medicine, especially the freezing technology promotes the conservative treatment of the gynecologic tumors. Based on all the aspects, we think that conservative therapy for gynecologic tumors also brings hope and trap to clinic diagnosis and treatment. In the future we need multidisciplinary collaboration, comprehensive evaluation and encourage patients to participate in multicenter clinical research. 【Key words 】 Gynecologic tumors; Conservative treatment [2] 近年来，妇科恶性肿瘤逐渐呈年轻化的趋势， 指南》 。然而，毋庸置疑的是，该领域目前仍有 并且随着诊疗手段的不断完善以及全民健康意识 诸多问题亟待解决，很多方面远未达成共识甚至存 增强，更多的妇科恶性肿瘤能够得到早期诊断。以 有争议。尽管目前已积累了丰富的临床资料和大宗 往妇科恶性肿瘤的处理主要是手术治疗（通常包含 的循证医学证据，凡此都不能改变这样一种事实， 子宫、双侧附件切除，盆腔淋巴结切除术）并辅以