不同促排卵方案在卵巢低反应助孕患者中的应用.pdfVIP

2013年6月第20卷第 17期 窑论 著 窑 不同促排卵方案在卵巢低反应助孕患者中的应用 黄 颖 广西医科大学第三附属医院生殖医疗中心袁广西南宁 530031 [摘要] 目的探讨不同促排卵方案在体外受精-胚胎移植的低反应患者中的应用价值遥 方法对广西医科大学 第三附属医院生殖中心2011年 1月耀2012年 12月250例351个周期的卵巢低反应患者的临床资料进行回顾 性分析袁根据不同的促排卵方案分组院微量长方案组90个周期渊A组冤尧拮抗剂方案组85个周期渊B组冤尧超短方 案组94个周期渊C组冤尧微刺激方案组82个周期渊D组冤袁比较分析各组的促排卵结局遥 结果各组间的临床妊 娠率尧获卵数尧成熟卵率尧受精率尧卵裂率尧优胚率尧周期取消率差异无统计学意义渊P跃0.05冤袁D组临床妊娠率略 高于其他3组曰HCG 日子宫内膜厚度尧P值尧LH值差异无统计学意义渊P跃0.05冤曰D组的促性腺激素渊Gn冤使用天 数及Gn用量明显少于其他3组袁差异有统计学意义渊P约0.05冤遥 结论对于卵巢低反应患者袁微刺激方案为较 好的治疗选择遥 [关键词] 体外受精-胚胎移植曰卵巢低反应曰促排卵 [中图分类号] R321.1 [文献标识码]A [文章编号] 1674-4721渊2013冤06渊b冤-0007-03 Application of different stimulate ovulation in patients with ovarian low reactionassistedreproduction HUANG Ying Reproductive Medical Center of the Third Affiliated Hospital of Guangxi Medical University,Guangxi Zhuang Au鄄 tonomous Region,Nanning 530031,China [Abstract]ObjectiveTo exploretheclinicalvalue ofdifferentovulation inductioninthe poor respondersduringIVF- ET. Methods A total of 250 patients in Reproductive Medical Center of the Third Affiliated Hospital of Guangxi Medical University with poor response were treated for 351 cycles,which were divided into four groups according to differentovulation inductionmethods:GnRH-aminidoselongprotocolgroupwhich includes90cycles (groupA), an鄄 tagonistprotocol groupwhich includes 85cycles (groupB),shortprotocol groupwhich includes94 cycles (group C), minimal stimulation (group D). The changes of related indexes were evaluated. Results No significant different was found among the four groups in the clinical pregnancy rate, number of oocytes retrieved,rate of mature eggs, fertiliza鄄 tionrate,cleavagerate,excellent embryorateandcyclecancellationrate (P跃0.05).The pregnancy rate of group Dwas a little higher th