乳腺浸润性导管癌的超声表现与病理及Id3mRNA表达关系的研究.pdfVIP

·527· ·I临床研究· 乳腺浸润性导管癌的超声表现与病理及 Id3mRNA表达关系的研究 郑敏穆丹梅戴险峰郑淼魏晓冬刘 磊杨木蕾 摘 要 目的初步探讨Id3mRNA表达与乳腺浸润性导管癌(IDc)超声表现之间的关系。方法应用实时荧光 定量RT—PCR检测36例IDC样本中Id3mRNA的表达，并与IDC超声表现对照分析。结果Id3mRNA在正常组织中的 像图表现与病理组织学变化密切相关。ⅢC的二维超声征象可在一定程度上反应Id3mRNA的表达水平。 关键词 浸润性导管癌；超声检查；病理组织学；Id基因；实时荧光定量RT—PCR 1he 0f carcinoma reJaaonsmp a弭咖0fId3mRNA缸breast劬锄瑚衄dlletal ultrmordc卿pe龃柚傀，阳m岫删the ZHENG Mulei Danmei，DAI Miao，WEI Lei，YANG Min，MU Xianfeng，ZHENGXiaodong，LIU The Clinical ofHarbin First MedicM 150001，China Hospital University，Harbin ABSTRACT To the betweentheuhrasonic ofthebreast ductalcarcino- Objectiveinvestigaterelationship appearance infiltrating the levelofId3mRNA．MethodsThereal—timefluorescent usedto mas(IOC)and R，r—PCR(RT—PCR)was expression quantitative The detectthe levelsofId3mRNAin36IDC．TheresultswEqe withtheuhra．fj()nicfeaturesofIDC．Results expression compared expres— waslowerin thanthatincarcinoma had intissuewithul— sionofId3mRNA normaltissues fissue(PO．01)．Id3mRNA highexpression trasonic of and duct Uhra．sonic is relatedto extension(Jp0．01)．Conclusion appearancespiclJlateIROnperipheral appearanceclosely inIDC．The levelofId3n承dNAcanbe