正交试验优选岗松挥发油β-环糊精包合物的制备工艺.pdf

正交试验优选岗松挥发油13一环糊精包合物的制备K-一t-t-- 中图分类号 R283；R944文献标识码 A 文章编号 1001—0408(2007)36—2830—03 摘要 目的：优选岗松挥发油p一环糊精包合物的制备工艺。方法：以岗松挥发油与p一环糊精的投料比、包合温度、搅拌时间为3 个因素，以包合物挥发油的利用率为筛选指标，采用正交试验进行优选。结果：岗松挥发油B一环糊精包合物制备的最佳工艺条件： 结论：岗松挥发油8一环糊精包合物的制备工艺切实可行，对提高岗松挥发油制剂的稳定性有一定的参考价值。 关键词 岗松挥发油；8一环糊精；包合物；正交试验；制备工艺 of ofOieumBaeckeae Inclusion Complexby OptimizationPreparationTechnology Oil—p—Cyclodextrin OrthogonalExperiment InstituteofTraditionalChinese JIANG Shaojie(Guangxi Medicine，Nanning Pingchuan，MAI na) CHEN TraditionalChineseMedical 530001，China) Meijiao(Guangxi College，Nanning ABSTRACT the ofOleumBaeckeae OBJECTIVE：Tooptimize technology preparation forOleumBaeckeae inclusion was complex．METHODS：Thepreparation oil一口一cyclodextrincomplex technology for and theratiooftheOleumBaeckeaeeoilto clathration byorthogonalexperimenttaking 8一cyclodextrin，thetemperature thedurationof asthreefactorsandwiththeutilizationratiooftheessentialoilin0leumBaeckeaeoilinclusion stirring complex Baeckeaeoilto asindex．RESULTS：The conditionwasasfollows：theratioofthe0leum optimaltechnological 8一cy— clodextrinintheinclusion was1；10：the forclathrationwas50℃，andthedurationof was2 complex temperature stirring as as ho