《医学遗传学》第七章群体遗传.pptVIP

* * * How many alleles do you have in common with... Your dad / your kids ? Your sister ? Your half brother ? Your niece ? Your first cousin ? -- How similar are you ? C D E F How many alleles do brother and sister share? D A E D E B 1/2 1/2 1/2 1/2 1/2 x 1/2 = 1/4 = fraction of alleles D E share from dad 1/2 x 1/2 = 1/4 = fraction of alleles D E share from mom 1/4 + 1/4 = 1/2= fraction of alleles D E share C D E F D G A E H D G E H B 1/2 1/2 1/2 1/2 1/2 1/2 1/2 1/2 1/2 x 1/2 x 1/2 x 1/2 = 1/16 = fraction of alleles G H share from common grandfather 1/2 x 1/2 x 1/2 x 1/2 = 1/16 = fraction