2007基因打靶技术_开启遗传学新纪元.pdfVIP

HEREDITAS (Beijing) 2007 11 , 29(11): ISSN 0253-9772 DOI: 10.1360/yc-007-1291 , , 100071 : , : ; ; ; Gene targeting: the beginning of a new era in genetics TENG Yan, YANG Xiao Genetic Laboratory of Development and Diseases, Beijing Institute of Biotechnology, Beijing 100071, China Abstract: Gene targeting, which allows the efficient modification of specific murine genes, plays important roles in eluci- dating p