Texture Analysis of Hippocampus for Epilepsy, in.pdfVIP

Texture analysis of hippocampus for epilepsy Kourosh Jafari-Khouzani,*a,b Mohammad-Reza Siadat,a,b Hamid Soltanian-Zadeh,b,c Kost Elisevichd aComputer Science Department, Wayne State University, Detroit, MI 48202, USA bRadiology Image Analysis Lab., Henry Ford Health System, Detroit, MI 48202, USA cElectrical and Computer Engineering Dept., University of Tehran, Tehran 14395, Iran dNeurosurgery Dept., Henry Ford Health System, Detroit, MI 48202, USA ABSTRACT This paper presents our recent study to evaluate how effectively the image texture information within the hippocampus structure can help the physicians to determine the candidates for epilepsy surgery. First we segment the hippocampus from T1-weighted images using our newly developed knowledge-based segmentation method. To extract the texture features we use multiwavelet, wavelet, and wavelet packet transforms. We calculate the energy and entropy features on each sub-band obtained by the wavelet decomposition. These texture features can be used by themselves or along with other features such as shape and average intensity to classify the hippocampi. The features are calculated on the T1- weighted and FLAIR MR images. Using these features, a clustering algorithm is applied to classify each hippocampus. To find the optimal basis, we use several different bases for wavelet and multiwavelet transforms, and compare the final classification performances, which is evaluated by correct classification rate (CCR). We use MRI of 14 epileptic patients along with their EEG results in our study. We use the pre-operative MR images of the patients who have already been determined as candidates for an epilepsy surgery using the gold standard (more costly and painful) metho