PGAβ-磷酸三钙骨组织工程支架的制备与性能.pdf

496 doi：lO．39690．issn．0253-9896．2012．05．025 PGA／13一磷酸三钙骨组织工程支架的制备与性能 李欣曹宏樊洪6 用改良溶液浇铸一离子沥滤的方法制备PGA／13一TCP骨组织T程复合支架材料。借助扫描电镜对其微结构进行观察， PGM0．39 并测试不同质量比的pGA／B—TCP骨组织f：程支架复合材料的物理、力学性能。结果：B组0．13g g肛TcP支 PGMO．13 架材料的抗压缩强度大于A组0．13g g PGA／13一TCP支架材料有望成为一种理想的骨组织工程支架材料。 关键词骨代用品生物医学丁程生物相容性材料支架羟基磷灰石类磷酸钙类 and ofPGA，B—Tricalciumof PreparationProperties Phosphate BoneTissue Scaffolds Engineering LIXin，CAO Hong，FANHong Medical 300070．China T／a彬n University．Tianjin Abstract fabricate tissue scaffoldsand Objective：ToporousPGA／13一tricalciumphosphate(Ij-TCP)forengineering testits PGA asscaffold sol— properties．Methods：Usingaadp-TCP chlorideas size：425-500 ra- vent，sodium porogen《particle Ixm)，thePGMl3-TCP，inI：l(Agroup)and1：3(Bgroup)weight of tios．scaffoldsfortissue werefabricatedmeansof microstructures engineering by solvent-castingparticulateleaching．The observed electron andmeehanic,dweretestedin thescaffoldswere usingscanning microscopy(SEM)．Thephysical properties B was inB PC,At0．39 that Aandgroups．Results：Thecompressivestrengthsignificantlyhighergroup(0．13g gB—TCP)than ofA PGM0．13 after were(731．283+55．