N-末端脑钠肽前体在舒张性心力衰竭患者中的表达水平.pdfVIP

Joun_lalofainicalMedicine，20儿．V01．18，№．3 中国临床医学2011年6月第18卷第3期Cllin∞e 317 ·论著· N．末端脑钠肽前体在舒张性心力衰竭患者中的表达水平 徐雪姣 (上海市闸北区北站医院心血管内科，上海200070) 摘要 疗，B组在常规治疗基础上加用倍他洛克治疗；6个月后复查血浆N，r-pr0BNP和超声心动图，比较治疗前后各项指标的差异。结 加用争受体阻滞荆可显著改善左室舒张功能。 关键词 N_末端脑钠肽前体；舒张性心力衰竭}伊受体阻滞剂 中图分类号R541．6+1文献标识码A The LevelofN—terminalProrBrainNatriureticinPatientwithDiastolicHeartFailure Expression Peptide i咒Z五口6Pi XL，X“巧i口DD8户口r芒7扎P扎￡o，C口rdzo抛sc“Z口，．MPdici，zP，B8iz^口咒Hos乡i￡nZDis￡，．if￡，S^口咒g^口i 200070。C^i竹口 Abstract the andtreatmentvalueofN—teminal natriuretic objective：Tostudydiagnostic pro-brain diastolicheart totalof80 aschronicheartfailurewere 42 failure(DHF)．Methods：A patientsdiagnosed entrolled，including cases caseswithsystolicheartfailure(SHF)and38caseswithdiastolicheartfailure(DHF)；another20 withnomalcardiac functionwereincludedascontrol was andserum levelsweremeasuredforaU group．Echocardiographyperformed NT-proBNP the 38cases DHFwerefurthersubdividedinto A(18 rou— with cases)andB(20 subjects．The Group Groupcases)，receiving tinetreatmentandroutine treatment The andserum were pluspBlocker respectively，echocardiographyNT—proBNPagain measuredafter6 theresultsbeforeandafterthetreatment． forthevalueofleftventricular months，tocompared Results：As enddiastolic ventricularend leftventricular