药物设计金点子改善水溶性的好方法 Nanonizationstrategiesforpoorly.pdfVIP

Drug Discovery Today Volume 00, Number 00 March 2010 REVIEWS N E E R C S T S Nanonization strategies for poorly O P s w e i water-soluble drugs v e R 1 1 2 3 Huabing Chen , Chalermchai Khemtong , Xiangliang Yang , Xueling Chang and Jinming Gao1 1 Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA 2 College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China 3 CAS Key Lab for Biomedical Effects of Nanomaterials and Nanosafety, Instit