辨病专方和辨证施治对酒精性肝损伤病证相合模型疗效对比.pdf

The curative effect comparison about disease differentiation based on the specified prescription and treatment based on syndrome differentiation towards the combination model of disease and syndrome of alcoholic hepatic injury Objective: Through investigating the effect of Weiganjiangmei prescription and treatment based on syndrome differentiation about combination model of disease and syndrome of alcoholic hepatic injury, explore its functional mechanism about anti-hepatic injury and advantages and disadvantages, summarize the prevalent treatment routine and provide the experimental and theoretical basis for standard medication. Methods: 200 Wistar male rats with alcohol intragastric administration. Produced the endoretention of damp heat and stagnation of liver-qi and deficiency of spleen model rats which were treated by TCM classical Prescription, specified prescription based on disease differentiation to compare effects. Through micro view to analyze the Weiganjiangmei Prescription advantages and disadvantages as well as its mechanism. Results: Successfully produced the endoretention of damp heat and stagnation of liver-qi and deficiency of spleen combination model rats of disease and syndrome of alcoholic hepatic injury .Weiganjiangmei decoction as well as specified prescription based syndrome differentiation had obvious therapeutical effect. In all the endoretention of dampheat treatment groups,Longdanxiegan decoction combined with Yinchenhao decotion could reduce the liver index,lowered down the GGF,FFA changed the liver structure.Weiganjiangmei combined with Longd