《Purification of Antibody Fragments CN》.pdf

Purification of Antibody Fragments 抗体片段的纯化 Outline 概况 Introduction 介绍 Applications 应用 • Fab • Dab • scFv Summary 总结 1 / GE / Development of MAb market 单抗市场的发展 Estimated sales of biologics, 2007-2014 200 180 160 Other rProteins 140 s Erythropoietins n 120 o Interferons i l l 100 i rProt vaccines B $ 80 Blood factors 60 Insulins 40 Monoclonal antibodies 20 0 2008 2009 2010 2011 2012 2013 2014 2015 What comes beyond MAb’s? 哪种产品将超越单抗？ Source: GE Healthcare estimations based on market analysis and company annual reports Antibody fragment market 抗体片段市场 100% e p 90% y 29 t t 80% n e 例 70% 53 m 比 g 的 60% a r scFv f 型 b 类 50% 100 50 Dabs A f 段 40% o n 片 30% 26 Fab o 体 i t r